Recombinant CD33 (Gemtuzumab Biosimilar) antibody
Reactivity: Human
FACS, IF
Host: Rabbit
Monoclonal
HP67-6
unconjugated
Recombinant Antibody
1 image
-
- Target See all CD33 (Gemtuzumab Biosimilar) products
- CD33 (Gemtuzumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Monoclonal
-
Conjugate
- This CD33 (Gemtuzumab Biosimilar) antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Specificity
- Recognises human CD33.
- Characteristics
-
OriginalSpeciesName: Human
OriginalFormat: IgG4
- Purification
- Purified antibody.
- Purity
- > 98 % as determined by SDS-PAGE
- Endotoxin Level
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogen
- Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
- Clone
- HP67-6
- Isotype
- IgG kappa
-
-
- Application Notes
- A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
- Comment
-
This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
- Target
- CD33 (Gemtuzumab Biosimilar)
- Abstract
- CD33 (Gemtuzumab Biosimilar) Products
- Synonyms
- SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, CD33 molecule antibody, CD33 antibody
- Target Type
- Biosimilar
- Background
- Siglec-3
- UniProt
- P20138
-
You are here:
