HFE2 antibody (AA 93-173)

Catalog No. ABIN566853

Product Details anti-HFE2 Antibody

Target: HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))

Binding Specificity: AA 93-173

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This HFE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse polyclonal antibody raised against a partial recombinant HFE2.

Sequence: GGCPPSQRLS RSERNRRGAI TIDTARRLCK EGLPVEDAYF HSCVFDVLIS GDPNFTVAAQ AALEDARAFL PDLEKLHLFP S

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HFE2 (NP_973733, 93 a.a. ~ 173 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-HFE2 antibody (ABIN566853)

Lakhal, Schödel, Townsend, Pugh, Ratcliffe, Mole: "Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis." in: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4090-7, (2011) (PubMed).

Target Details for HFE2

Target: HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))

Alternative Name: HFE2 (HFE2 Products)

Synonyms: HFE2A antibody, HJV antibody, JH antibody, RGMC antibody, HFE2 antibody, DKFZp468F2322 antibody, 2310035L15Rik antibody, 5230400G09Rik antibody, AI414844 antibody, AI789733 antibody, DL-M antibody, Rgmc antibody, hemojuvelin antibody, RGMr antibody, hjv antibody, id:ibd3464 antibody, wu:fb38f10 antibody, zgc:136698 antibody, hemochromatosis type 2 (juvenile) antibody, hemochromatosis type 2 antibody, HFE2 antibody, Hfe2 antibody, hfe2 antibody

Background: Full Gene Name: hemochromatosis type 2 (juvenile)
Synonyms: HFE2A,HJV,JH,MGC23953,RGMC

Gene ID: 148738

NCBI Accession: NM_202004

Pathways: Transition Metal Ion Homeostasis