RAPGEF4 antibody (Middle Region)

Catalog No. ABIN5672627

Product Details anti-RAPGEF4 Antibody

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPGEF4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LEKIVKQISE DAKAPQKKHK VLLQQFNTGD ERAQKRQPIR GSDEVLFKVY

Characteristics: This is a rabbit polyclonal antibody against RPGF4. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human RPGF4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAPGEF4

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Alternative Name: RPGF4 (RAPGEF4 Products)

Synonyms: RAPGEF4 antibody, CAMP-GEFII antibody, CGEF2 antibody, EPAC2 antibody, Nbla00496 antibody, 1300003D15Rik antibody, 5730402K07Rik antibody, 6330581N18Rik antibody, EPAC 2 antibody, Epac-2 antibody, Epac2 antibody, mKIAA4040 antibody, CAMPS antibody, Cgef2 antibody, Rap guanine nucleotide exchange factor 4 antibody, rap guanine nucleotide exchange factor 4 antibody, Rap guanine nucleotide exchange factor (GEF) 4 antibody, RAPGEF4 antibody, LOC579050 antibody, LOC100551109 antibody, PTRG_05798 antibody, Rapgef4 antibody

Background: RPGF4 is a guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. It seems not to activate RAB3A. Involved in cAMP-dependent, PKA- independent exocytosis through interaction with RIMS2.

Alias Symbols: RAPGEF4, CGEF2, EPAC2,

Protein Interaction Partner: C16orf45, SWAP70, ZC3H11A, BZRAP1, TRAF2, ATXN1, RIMS2, MAP1A, RRAS2, RAP2A, RAP1A, ABCC8,

Protein Size: 696

Gene ID: 11069

Pathways: Hormone Transport, Smooth Muscle Cell Migration