Family with Sequence Similarity 162, Member A (FAM162A) (Middle Region) antibody

Details for Product No. ABIN5673864
Target
Binding Specificity
Middle Region
8
1
1
Reactivity
Human
10
8
Host
Rabbit
10
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Western Blotting (WB)
10
7
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FAM162A
Sequence LCERDVSSSL RLTRSSDLKR INGFCTKPQE SPGAPSRTYN RVPLHKPTDW
Purification Affinity purified
Target
Alternative Name FAM162A (FAM162A Antibody Abstract)
Background Proposed to be involved in regulation of apoptosis, the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus, however, the involvement of caspases has been reported conflictingly.

Alias Symbols: E2IG5, HGTD-P, C3orf28

Protein Size: 154
Gene ID 26355
NCBI Accession NM_014367, NP_055182
UniProt Q96A26
Pathways Positive Regulation of Endopeptidase Activity, SARS-CoV-2 Protein Interactome
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.