DNAJB11 antibody (AA 25-130) (HRP)

Catalog No. ABIN5675019

This Rabbit Polyclonal antibody specifically detects DNAJB11 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for DNAJB11 antibody (AA 25-130) (HRP) (ABIN5675019)

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJB11 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-DNAJB11 Antibody (HRP)

Binding Specificity: AA 25-130

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNAJB11

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DNAJB11

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Alternative Name: DNAJB11

Background:

Synonyms: DnaJ homolog subfamily B member 11, DNAJB11, APOBEC1-binding protein 2, ABBP-2, DnaJ protein homolog 9, ER-associated DNAJ, EDJ, ERJ3, HDJ9, PSEC0121, UNQ537/PRO1080

Background: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

Gene ID: 51726

UniProt: Q9UBS4

Pathways: ER-Nucleus Signaling