PTPRM antibody (AA 565-742)
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- Target See all PTPRM Antibodies
- PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
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Binding Specificity
- AA 565-742
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PTPRM antibody is un-conjugated
- Application
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human PTPRM (AA: extra 565-742) expressed in E. coli.
- Clone
- 8F1C10
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
- Alternative Name
- PTPRM (PTPRM Products)
- Synonyms
- cb984 antibody, ptprm antibody, zgc:110218 antibody, PTPRM antibody, p-ptp-mu antibody, ptprl1 antibody, r-ptpu antibody, rptpm antibody, rptpu antibody, PTPRL1 antibody, R-PTP-MU antibody, RPTPM antibody, RPTPU antibody, hR-PTPu antibody, RPTPmu antibody, mKIAA4044 antibody, protein tyrosine phosphatase, receptor type, M, a antibody, protein tyrosine phosphatase, receptor type M antibody, protein tyrosine phosphatase, receptor type, M, b antibody, receptor-type tyrosine-protein phosphatase mu antibody, protein tyrosine phosphatase, receptor type, M antibody, ptprma antibody, PTPRM antibody, ptprmb antibody, ptprm antibody, LOC100550127 antibody, LOC100564083 antibody, Ptprm antibody
- Background
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Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Aliases: RPTPM, RPTPU, PTPRL1, hR-PTPu, R-PTP-MU
- Molecular Weight
- 163.7 kDa
- Gene ID
- 5797
- HGNC
- 2215
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