CEACAM1 antibody (AA 65-201)

Catalog No. ABIN5684132

Product Details anti-CEACAM1 Antibody

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Binding Specificity: AA 65-201

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEACAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CD66A (AA: extra 65-201) expressed in E. coli.

Clone: 4F3B2

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Alternative Name: CD66A (CEACAM1 Products)

Synonyms: BGP antibody, BGP1 antibody, BGPI antibody, CD66e antibody, CEA antibody, zeh0068 antibody, hm:zeh0068 antibody, CEACAM8 antibody, CEACAM1 antibody, MGC142545 antibody, BGPR antibody, Bgp antibody, CD66a antibody, Ccam1 antibody, Bgp1 antibody, C-CAM antibody, Cc1 antibody, Cea-1 antibody, Cea-7 antibody, Cea1 antibody, Cea7 antibody, Hv-2 antibody, Hv2 antibody, MHVR antibody, MHVR1 antibody, Mhv-1 antibody, bb-1 antibody, mCEA1 antibody, mmCGM1 antibody, mmCGM1a antibody, mmCGM2 antibody, carcinoembryonic antigen related cell adhesion molecule 1 antibody, carcinoembryonic antigen related cell adhesion molecule 5 antibody, carcinoembryonic antigen-related cell adhesion molecule 1 antibody, carcinoembryonic antigen-related cell adhesion molecule 6 antibody, CEACAM1 antibody, CEACAM5 antibody, ceacam1 antibody, Ceacam1 antibody, LOC101103343 antibody

Background:

Description: This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Aliases: CEACAM1, BGP, BGP1, BGPI

Molecular Weight: 57.6 kDa

Gene ID: 634

HGNC: 634