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DOCK8 antibody (C-Term)
DOCK8
Reactivity: Human, Mouse, Rat
WB, ELISA, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DOCK8 Antibody
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Target
See all DOCK8 Antibodies
DOCK8
(Dedicator of Cytokinesis 8 (DOCK8))
Binding Specificity
All epitopes for DOCK8 antibodies
C-Term
Reactivity
Human, Mouse, Rat
Host
All hosts for DOCK8 antibodies
Rabbit
Clonality
All clonalities for DOCK8 antibodies
Polyclonal
Conjugate
All conjugates for DOCK8 antibodies
This DOCK8 antibody is un-conjugated
Application
All applications for DOCK8 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
DOCK8 antibody is human, mouse and rat reactive. Multiple isoforms of DOCK8 are known to exist.
Purification
DOCK8 antibody is affinity chromatography purified via peptide column.
Immunogen
DOCK8 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DOCK8. The immunogen is located within the last 50 amino acids of DOCK8.
Isotype
IgG
Top Product
Discover our top product DOCK8 Primary Antibody
Alternatives
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Application Details
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Application Notes
DOCK8 antibody can be used for detection of DOCK8 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
DOCK8 antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
DOCK8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target Details for DOCK8
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Target
DOCK8
(Dedicator of Cytokinesis 8 (DOCK8))
Alternative Name
DOCK8 (DOCK8 Products )
Synonyms
im:7154406 antibody, si:dkey-91m11.1 antibody, MRD2 antibody, ZIR8 antibody, 1200017A24Rik antibody, 5830472H07Rik antibody, A130095G14Rik antibody, AI461977 antibody, dedicator of cytokinesis 8 antibody, dock8 antibody, DOCK8 antibody, Dock8 antibody
Background
The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors (1). DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse (reviewed in 2). Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome (3).
Molecular Weight
Predicted: 166, 220, 231 kDa Observed: 220, 230 kDa
Gene ID
81704
NCBI Accession
NP_982272
UniProt
Q8NF50
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