Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) antibody
SCD1
Reactivity: Mouse
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
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- Target See all Stearoyl-Coenzyme A Desaturase 1 (SCD1) Antibodies
- Stearoyl-Coenzyme A Desaturase 1 (SCD1)
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Binding Specificity
- AA 21-33
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
- Application
- Western Blotting (WB), ELISA
- Specificity
- Recognizes mouse SCD1. Detects a band of ~41 kDa by Western Blot.
- Immunogen
- Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1.
- Top Product
- Discover our top product SCD1 Primary Antibody
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anti-Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) antibody
SCD1 Reactivity: Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL, suggested blocking and dilution buffer is PBST containing 0.05 % Tween 20 and 5 % skim milk, suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Preservative
- Without preservative
- Storage
- -20 °C
- Storage Comment
- Stable for at least 6 months after receipt when stored at -20°C.
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- Target
- Stearoyl-Coenzyme A Desaturase 1 (SCD1)
- Alternative Name
- Stearoyl-CoA Desaturase-1 (SCD1 Products)
- Synonyms
- AA589638 antibody, AI265570 antibody, Scd antibody, Scd-1 antibody, ab antibody, stearoyl-Coenzyme A desaturase 1 antibody, Scd1 antibody
- Background
- Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.
- Gene ID
- 20249
- UniProt
- P13516
- Pathways
- Brown Fat Cell Differentiation
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