CNOT7 antibody

Catalog No. ABIN5697249

Product Details anti-CNOT7 Antibody

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogen: CCR4-NOT transcription complex, subunit 7

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CNOT7

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Alternative Name: CNOT7 (CNOT7 Products)

Synonyms: CNOT7 antibody, CAF1 antibody, fd59c07 antibody, fj07d05 antibody, wu:fd59c07 antibody, wu:fj07d05 antibody, zgc:153168 antibody, caf1 antibody, Caf1a antibody, hCAF-1 antibody, AU022737 antibody, CAF-1 antibody, Caf1 antibody, Pop2 antibody, CCR4-NOT transcription complex subunit 7 antibody, ccr4-not transcription complex, subunit 7 antibody, CCR4-NOT transcription complex, subunit 7 antibody, ccr4-not transcription complex, subunit 7, putative antibody, CCR4-NOT transcription complex subunit 7 S homeolog antibody, CNOT7 antibody, CNL04550 antibody, GL50803_10606 antibody, GL50803_8209 antibody, CGB_D2510C antibody, cnot7 antibody, cnot7.S antibody, Cnot7 antibody

Background: Synonyms:CAF1 Background:Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

Molecular Weight: 33-35 kDa

Gene ID: 29883

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization