TSHZ3 antibody

Catalog No. ABIN5698742

Product Details anti-TSHZ3 Antibody

Target: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSHZ3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: teashirt zinc finger homeobox 3

Isotype: IgG

Application Details

Application Notes: WB : 1:200-1:2000

Comment:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09046( TSHZ3 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TSHZ3

Target: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Alternative Name: TSHZ3 (ZNF537 Products)

Synonyms: ZNF537 antibody, A630038G13Rik antibody, Tsh3 antibody, Zfp537 antibody, mKIAA1474 antibody, teashirt3 antibody, TSH3 antibody, teashirt zinc finger homeobox 3 antibody, teashirt zinc finger family member 3 antibody, TSHZ3 antibody, Tshz3 antibody

Background: Synonyms:FLJ54422, KIAA1474, Teashirt homolog 3, TSH3, TSHZ3, Zinc finger protein 537, ZNF537 Background:Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus(nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator(RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.

Molecular Weight: 87kDa

Gene ID: 57616

UniProt: Q63HK5

Pathways: Regulation of Muscle Cell Differentiation