TSHZ3 antibody
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- Target See all TSHZ3 (ZNF537) Antibodies
- TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TSHZ3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Immunogen
- teashirt zinc finger homeobox 3
- Isotype
- IgG
- Top Product
- Discover our top product ZNF537 Primary Antibody
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- Application Notes
- WB : 1:200-1:2000
- Comment
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09046( TSHZ3 Antibody) at dilution of 1:600
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))
- Alternative Name
- TSHZ3 (ZNF537 Products)
- Synonyms
- ZNF537 antibody, A630038G13Rik antibody, Tsh3 antibody, Zfp537 antibody, mKIAA1474 antibody, teashirt3 antibody, TSH3 antibody, teashirt zinc finger homeobox 3 antibody, teashirt zinc finger family member 3 antibody, TSHZ3 antibody, Tshz3 antibody
- Background
- Synonyms:FLJ54422, KIAA1474, Teashirt homolog 3, TSH3, TSHZ3, Zinc finger protein 537, ZNF537 Background:Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus(nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator(RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.
- Molecular Weight
- 87kDa
- Gene ID
- 57616
- UniProt
- Q63HK5
- Pathways
- Regulation of Muscle Cell Differentiation
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