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PSTPIP1 antibody

PSTPIP1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5698979
  • Target See all PSTPIP1 Antibodies
    PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
    Reactivity
    • 25
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 23
    • 2
    Rabbit
    Clonality
    • 23
    • 2
    Polyclonal
    Conjugate
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This PSTPIP1 antibody is un-conjugated
    Application
    • 25
    • 18
    • 13
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Immunogen
    proline-serine-threonine phosphatase interacting protein 1
    Isotype
    IgG
    Top Product
    Discover our top product PSTPIP1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab06903(PSTPIP1 antibody) at dilution of 1:300

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze / thaw cycles.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
    Alternative Name
    PSTPIP1 (PSTPIP1 Products)
    Synonyms
    cd2bp1 antibody, cd2bp1l antibody, cd2bp1s antibody, h-pip antibody, papas antibody, pstpip antibody, PSTPIP1 antibody, CD2BP1 antibody, CD2BP1L antibody, CD2BP1S antibody, H-PIP antibody, PAPAS antibody, PSTPIP antibody, def-2 antibody, proline-serine-threonine phosphatase interacting protein 1 antibody, proline-serine-threonine phosphatase interacting protein 1 S homeolog antibody, proline-serine-threonine phosphatase-interacting protein 1 antibody, PSTPIP1 antibody, pstpip1.S antibody, pstpip1 antibody, Pstpip1 antibody
    Background
    Synonyms:CD2BP1 Background:This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response.
    Gene ID
    9051
    UniProt
    O43586
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