TIMM8A/DDP antibody

Catalog No. ABIN5699077

Product Details anti-TIMM8A/DDP Antibody

Target: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM8A/DDP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: translocase of inner mitochondrial membrane 8 homolog A (yeast)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TIMM8A/DDP

Target: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Alternative Name: TIMM8A (TIMM8A Products)

Synonyms: TIMM8A antibody, ddp antibody, tim8a antibody, timm8a antibody, DDP antibody, DDP1 antibody, DFN1 antibody, MTS antibody, TIM8 antibody, im:6896085 antibody, zgc:100916 antibody, Ddp1 antibody, Timm8a antibody, DXHXS1274E antibody, Fci-12 antibody, Tim8a antibody, translocase of inner mitochondrial membrane 8 homolog A (yeast) antibody, translocase of inner mitochondrial membrane 8A antibody, translocase of inner mitochondrial membrane 8 homolog A1 (yeast) antibody, translocase of inner mitochondrial membrane 8A1 antibody, TIMM8A antibody, timm8a antibody, Timm8a1 antibody

Background: Synonyms:DDP, DDP1, TIM8A Background:Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery(SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.

Gene ID: 1678

UniProt: O60220