MED12 antibody

Catalog No. ABIN5699865

Product Details anti-MED12 Antibody

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED12 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Immunogen: mediator complex subunit 12

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MED12

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Alternative Name: MED12 (MED12 Products)

Synonyms: ARC240 antibody, CAGH45 antibody, FGS1 antibody, HOPA antibody, MED12S antibody, OHDOX antibody, OKS antibody, OPA1 antibody, TNRC11 antibody, TRAP230 antibody, 230kDa antibody, Mopa antibody, OPA-1 antibody, Tnrc11 antibody, Trap230 antibody, mediator complex subunit 12 antibody, MED12 antibody, Med12 antibody, med12 antibody

Background: Synonyms:ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230 Background:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

Molecular Weight: 230 kDa

Gene ID: 9968

UniProt: Q93074

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation