CC2D1A antibody
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- Target See all CC2D1A Antibodies
- CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CC2D1A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Immunogen
- coiled-coil and C2 domain containing 1A
- Isotype
- IgG
- Top Product
- Discover our top product CC2D1A Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01335(CC2D1A antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
- Alternative Name
- CC2D1A (CC2D1A Products)
- Synonyms
- mrt3 antibody, freud-1 antibody, FREUD-1 antibody, Freud-1/Aki1 antibody, MRT3 antibody, BC016188 antibody, Freud-1 antibody, Tape antibody, RGD1306108 antibody, coiled-coil and C2 domain containing 1A antibody, CC2D1A antibody, cc2d1a antibody, Cc2d1a antibody
- Background
- Synonyms:AKI1 Background:Transcription factor that binds specifically to the DRE(dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses(By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.
- Molecular Weight
- 130 kDa, 104 kDa
- Gene ID
- 54862
- UniProt
- Q6P1N0
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