STING/TMEM173 antibody

Catalog No. ABIN5701799

The Rabbit Polyclonal anti-STING/TMEM173 antibody has been validated for WB, ELISA, IHC, FACS, IP and IF. It is suitable to detect STING/TMEM173 in samples from Human, Mouse and Rat.

Quick Overview for STING/TMEM173 antibody (ABIN5701799)

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STING/TMEM173 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-STING/TMEM173 Antibody

Immunogen: transmembrane protein 173

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab08759(TMEM173 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for STING/TMEM173

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Alternative Name: TMEM173

Background: Synonyms:ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING Background:This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Gene ID: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response