DENND1A antibody

Catalog No. ABIN5701845

Product Details anti-DENND1A Antibody

Target: DENND1A (DENN/MADD Domain Containing 1A (DENND1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND1A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Immunogen: DENN/MADD domain containing 1A

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for DENND1A

Target: DENND1A (DENN/MADD Domain Containing 1A (DENND1A))

Alternative Name: DENND1A (DENND1A Products)

Synonyms: RGD1307927 antibody, FAM31A antibody, KIAA1608 antibody, RP11-230L22.3 antibody, 6030446I19Rik antibody, connecdenn antibody, fam31a antibody, DENN domain containing 1A antibody, DENN/MADD domain containing 1A antibody, DENN domain-containing protein 1A antibody, DENN domain containing 1A S homeolog antibody, Dennd1a antibody, DENND1A antibody, dennd1a antibody, LOC100512328 antibody, dennd1a.S antibody

Background: Synonyms:FAM31A, KIAA1608 Background:Guanine nucleotide exchange factor(GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes(PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates(PtdInsPs), with some preference for PtdIns(3)P(By similarity).

Molecular Weight: 111 kDa, 64 kDa

Gene ID: 57706

UniProt: Q8TEH3