USP44 antibody
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- Target See all USP44 Antibodies
- USP44 (Ubiquitin Specific Peptidase 44 (USP44))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This USP44 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Immunogen
- ubiquitin specific peptidase 44
- Isotype
- IgG
- Top Product
- Discover our top product USP44 Primary Antibody
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- Application Notes
- WB : 1:500-1:5000
- Comment
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human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09334(USP44 antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- USP44 (Ubiquitin Specific Peptidase 44 (USP44))
- Alternative Name
- USP44 (USP44 Products)
- Synonyms
- usp44 antibody, USP49 antibody, E430004F17Rik antibody, zgc:55661 antibody, ubiquitin specific peptidase 44 antibody, ubiquitin specific peptidase 44 L homeolog antibody, ubiquitin specific peptidase 44 S homeolog antibody, USP44 antibody, usp44.L antibody, usp44.S antibody, usp44 antibody, Usp44 antibody
- Background
- Synonyms:Deubiquitinating enzyme 44, DKFZp434D0127, FLJ14528, Ubiquitin thiolesterase 44, USP44 Background:Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B(H2BK120ub1) ubiquitination.
- Molecular Weight
- 145kDa
- Gene ID
- 84101
- UniProt
- Q9H0E7
- Pathways
- M Phase
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