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BEX2 antibody

BEX2 Reactivity: Human, Mouse, Rat ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5702196
  • Target See all BEX2 Antibodies
    BEX2 (Brain Expressed X-Linked 2 (BEX2))
    Reactivity
    Human, Mouse, Rat
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BEX2 antibody is un-conjugated
    Application
    • 7
    • 4
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    Immunogen
    brain expressed X-linked 2
    Isotype
    IgG
    Top Product
    Discover our top product BEX2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    human brain tissue were subjected to SDS PAGE followed by western blot with FNab00884(BEX2 antibody) at dilution of 1:500

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze / thaw cycles.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    BEX2 (Brain Expressed X-Linked 2 (BEX2))
    Alternative Name
    BEX2 (BEX2 Products)
    Synonyms
    BEX1 antibody, DJ79P11.1 antibody, AL024066 antibody, Bex1 antibody, EG2RVC antibody, brain expressed X-linked 2 antibody, BEX2 antibody, Bex2 antibody
    Background
    Synonyms:BEX1, BEX1/2, BEX2, brain expressed X linked 2, hBex2, Protein BEX2 Background:Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94 % . This antibody detects both BEX1 and BEX2.
    Gene ID
    84707
    UniProt
    Q9BXY8
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