TBCD antibody

Catalog No. ABIN5702398

Product Details anti-TBCD Antibody

Target: TBCD (Tubulin Folding Cofactor D (TBCD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBCD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogen: tubulin folding cofactor D

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TBCD

Target: TBCD (Tubulin Folding Cofactor D (TBCD))

Alternative Name: TBCD (TBCD Products)

Synonyms: SSD-1 antibody, tfcD antibody, 2310057L06Rik antibody, A030005L14Rik antibody, mKIAA0988 antibody, tubulin folding cofactor D antibody, tubulin-specific chaperone d antibody, TBCD antibody, Tbcd antibody

Background: Synonyms:KIAA0988, SSD1, TFCD Background:Tubulin-folding protein, involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin(TUBB). Acts as a GTPase-activating protein(GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.

Gene ID: 6904

UniProt: Q9BTW9

Pathways: Cell-Cell Junction Organization