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EDEM2 antibody

EDEM2 Reactivity: Human, Mouse, Rat ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5702421
  • Target See all EDEM2 Antibodies
    EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))
    Reactivity
    Human, Mouse, Rat
    Host
    • 25
    • 4
    Rabbit
    Clonality
    • 26
    • 3
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EDEM2 antibody is un-conjugated
    Application
    • 23
    • 13
    • 13
    • 12
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Immunogen
    ER degradation enhancer, mannosidase alpha-like 2
    Isotype
    IgG
    Top Product
    Discover our top product EDEM2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze / thaw cycles.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))
    Alternative Name
    EDEM2 (EDEM2 Products)
    Synonyms
    C20orf31 antibody, C20orf49 antibody, bA4204.1 antibody, 9530090G24Rik antibody, AI327354 antibody, RGD1303074 antibody, MGC88910 antibody, DKFZp459A0314 antibody, ER degradation enhancing alpha-mannosidase like protein 2 antibody, ER degradation enhancer, mannosidase alpha-like 2 antibody, EDEM2 antibody, Edem2 antibody, edem2 antibody
    Background
    Synonyms:C20orf31, C20orf49 Background:Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
    Molecular Weight
    60-65 kDa
    Gene ID
    55741
    UniProt
    Q9BV94
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