LONP1 antibody

Catalog No. ABIN5702491

Product Details anti-LONP1 Antibody

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This LONP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: lon peptidase 1, mitochondrial

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04821( LONP1 Antibody) at dilution of 1:5000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Alternative Name: LONP1 (LONP1 Products)

Synonyms: PRSS15 antibody, prss15 antibody, fc64d11 antibody, wu:fc64d11 antibody, LON antibody, LONP antibody, LonHS antibody, PIM1 antibody, hLON antibody, 1200017E13Rik antibody, Prss15 antibody, Lon antibody, lon peptidase 1, mitochondrial antibody, ATP-dependent Lon protease antibody, LONP1 antibody, lonp1 antibody, Lonp1 antibody, PIM1 antibody

Background: Synonyms:PRSS15 Background:ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory(StAR) protein.

Molecular Weight: 100 kDa

Gene ID: 9361

UniProt: P36776