KATNB1 antibody

Catalog No. ABIN5703051

Product Details anti-KATNB1 Antibody

Target: KATNB1 (Katanin P80 (WD Repeat Containing) Subunit B 1 (KATNB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KATNB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogen: katanin p80 (WD repeat containing) subunit B 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for KATNB1

Target: KATNB1 (Katanin P80 (WD Repeat Containing) Subunit B 1 (KATNB1))

Alternative Name: KATNB1 (KATNB1 Products)

Synonyms: kat antibody, MGC69344 antibody, KAT antibody, wu:fj32f02 antibody, wu:fj65h01 antibody, zgc:56071 antibody, 2410003J24Rik antibody, katanin regulatory subunit B1 antibody, katanin p80 subunit antibody, katanin p80 WD40 repeat-containing subunit B1 antibody, katanin regulatory subunit B1 L homeolog antibody, katanin p80 (WD repeat containing) subunit B 1 antibody, katanin p80 (WD40-containing) subunit B 1 antibody, Katnb1 antibody, KATNB1 antibody, katnb1 antibody, LOC5567105 antibody, PF15 antibody, katnb1.L antibody

Background: Synonyms:KAT, Katanin p80 subunit B1, KATNB1, p80 katanin Background:Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.

Molecular Weight: 72-80 kDa

Gene ID: 10300

UniProt: Q9BVA0

Pathways: Microtubule Dynamics