CBY1/PGEA1 antibody
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- Target See all CBY1/PGEA1 (CBY1) Antibodies
- CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CBY1/PGEA1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunoprecipitation (IP)
- Immunogen
- chibby homolog 1 (Drosophila)
- Isotype
- IgG
- Top Product
- Discover our top product CBY1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab01334(CBY1 antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))
- Alternative Name
- CBY1 (CBY1 Products)
- Synonyms
- chibby antibody, cby antibody, arb1 antibody, pgea1 antibody, pigea14 antibody, pigea-14 antibody, hs508i15a antibody, C22orf2 antibody, CBY antibody, HS508I15A antibody, PGEA1 antibody, PIGEA-14 antibody, PIGEA14 antibody, 1110014P06Rik antibody, PGEA14 antibody, Pgea1 antibody, chibby homolog 1 S homeolog antibody, chibby homolog 1 antibody, chibby family member 1, beta catenin antagonist antibody, cby1.S antibody, cby1 antibody, CBY1 antibody, Cby1 antibody
- Background
- Synonyms:ARB1, C22orf2, CBY, PGEA1 Background:Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
- Molecular Weight
- 30-35 kDa
- Gene ID
- 25776
- UniProt
- Q9Y3M2
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