NUDT3 antibody

Catalog No. ABIN5704047

Product Details anti-NUDT3 Antibody

Target: NUDT3 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 3 (NUDT3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUDT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: nudix (nucleoside diphosphate linked moiety X)-type motif 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for NUDT3

Target: NUDT3 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 3 (NUDT3))

Alternative Name: NUDT3 (NUDT3 Products)

Synonyms: DIPP antibody, DIPP-1 antibody, DIPP1 antibody, 1110011B09Rik antibody, AA960325 antibody, Dipp antibody, NUDT3 antibody, zgc:55746 antibody, zgc:103443 antibody, nudix hydrolase 3 antibody, nudix (nucleotide diphosphate linked moiety X)-type motif 3 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 3a antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 3b antibody, NUDT3 antibody, Nudt3 antibody, nudt3a antibody, nudt3b antibody

Background: Synonyms:DIPP, DIPP1 Background:Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5(diphosphoinositol pentakisphosphate) and [PP]2-InsP4(bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6(inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.

Molecular Weight: 20-30 kDa

Gene ID: 11165

UniProt: O95989