MEX3C antibody

Catalog No. ABIN5704307

Product Details anti-MEX3C Antibody

Target: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEX3C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: mex-3 homolog C (C. elegans)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab05145(MEX3C antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MEX3C

Target: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Alternative Name: MEX3C (MEX3C Products)

Synonyms: Rkhd2 antibody, RKHD2 antibody, rkhd2 antibody, bm-013 antibody, rnf194 antibody, MEX-3C antibody, RNF194 antibody, A130001D14Rik antibody, BC035207 antibody, BM-013 antibody, mex-3 RNA binding family member C antibody, mex3 RNA binding family member C antibody, Mex3c antibody, MEX3C antibody, mex3c antibody

Background: Synonyms:RKHD2, RNF194 Background:E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.

Molecular Weight: 69 kDa

Gene ID: 51320

UniProt: Q5U5Q3