STOML2 antibody

Catalog No. ABIN5704412

Product Details anti-STOML2 Antibody

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This STOML2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Immunogen: stomatin (EPB72)-like 2

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab08347(STOML2 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for STOML2

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Alternative Name: STOML2 (STOML2 Products)

Synonyms: zgc:63505 antibody, MGC116533 antibody, 0610038F01Rik antibody, MSLP2 antibody, SLP-2 antibody, stomatin (EPB72)-like 2 antibody, stomatin like 2 antibody, stomatin like 2 L homeolog antibody, stomatin (Epb7.2)-like 2 antibody, stoml2 antibody, STOML2 antibody, stoml2.L antibody, Stoml2 antibody

Background: Synonyms:EPB72 like protein 2, HSPC108, SLP 2, SLP2, stomatin (EPB72) like 2, Stomatin like protein 2, STOML2 Background:Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.

Gene ID: 30968

UniProt: Q9UJZ1

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection