SUPV3L1 antibody

Catalog No. ABIN5704647

Product Details anti-SUPV3L1 Antibody

Target: SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUPV3L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA

Immunogen: suppressor of var1, 3-like 1 (S. cerevisiae)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SUPV3L1

Target: SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))

Alternative Name: SUPV3L1 (SUPV3L1 Products)

Synonyms: SUV3 antibody, 6330443E10Rik antibody, wu:fc19b02 antibody, wu:fe37e06 antibody, Suv3 like RNA helicase antibody, suppressor of var1, 3-like 1 (S. cerevisiae) antibody, SUV3-like helicase antibody, SUPV3L1 antibody, Supv3l1 antibody, supv3l1 antibody

Background: Synonyms:SUV3 Background:Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome(mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded(ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria, regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.

Gene ID: 6832

UniProt: Q8IYB8