STK36 antibody
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- Target See all STK36 Antibodies
- STK36 (serine/threonine Kinase 36 (STK36))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This STK36 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogen
- serine/threonine kinase 36, fused homolog (Drosophila)
- Isotype
- IgG
- Top Product
- Discover our top product STK36 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08335(STK36 antibody) at dilution of 1:300
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- STK36 (serine/threonine Kinase 36 (STK36))
- Alternative Name
- STK36 (STK36 Products)
- Synonyms
- FU antibody, fused-like antibody, 1700112N14Rik antibody, B930045J24 antibody, Fused antibody, mKIAA1278 antibody, fu antibody, si:dkey-180i4.3 antibody, zgc:152944 antibody, serine/threonine kinase 36 antibody, serine/threonine kinase 36 (fused homolog, Drosophila) antibody, STK36 antibody, Stk36 antibody, stk36 antibody
- Background
- Synonyms:KIAA1278 Background:Serine/threonine protein kinase which plays an important role in the sonic hedgehog(Shh) pathway by regulating the activity of GLI transcription factors(PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization(PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur(PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function(By similarity). Essential for construction of the central pair apparatus of motile cilia.
- Gene ID
- 27148
- UniProt
- Q9NRP7
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