SIKE1 antibody

Catalog No. ABIN5705251

Product Details anti-SIKE1 Antibody

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIKE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: suppressor of IKK epsilon

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07867(SIKE1 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SIKE1

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Alternative Name: SIKE1 (SIKE1 Products)

Synonyms: SIKE antibody, 2810005O12Rik antibody, 5730470L24Rik antibody, AI450236 antibody, AI839862 antibody, Sike antibody, Sikeb antibody, RGD1311316 antibody, suppressor of IKBKE 1 antibody, SIKE1 antibody, Sike1 antibody

Background: Synonyms:SIKE Background:Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements(ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.

Gene ID: 80143

UniProt: Q9BRV8