CXXC5 antibody

Catalog No. ABIN5705576

Product Details anti-CXXC5 Antibody

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXXC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: CXXC finger 5

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CXXC5

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Alternative Name: CXXC5 (CXXC5 Products)

Synonyms: 4930415K17Rik antibody, CF5 antibody, RINF antibody, WID antibody, CXXC finger 5 antibody, CXXC finger protein 5 antibody, Cxxc5 antibody, CXXC5 antibody

Background: Synonyms: Background:May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells(By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions(4 % oxygen), as well as normoxia conditions(20 % oxygen)(PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ(PubMed:23303788).

Molecular Weight: 35-40 kDa

Gene ID: 51523

UniProt: Q7LFL8