H3F3B antibody

Catalog No. ABIN5705915

Product Details anti-H3F3B Antibody

Target: H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H3F3B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: H3 histone, family 3B (H3.3B)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for H3F3B

Target: H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))

Alternative Name: H3F3B (H3F3B Products)

Synonyms: 9430068D06Rik antibody, H3.3B antibody, H3 histone, family 3B antibody, H3 histone family member 3B antibody, H3f3b antibody, H3F3B antibody

Background: Synonyms:H3.3B Background:Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Molecular Weight: 17 kDa

Gene ID: 3021

UniProt: P84243