AMH antibody (AA 75-141)

Catalog No. ABIN5708062

Product Details anti-AMH Antibody

Target: AMH (Anti-Mullerian Hormone (AMH))

Binding Specificity: AA 75-141

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMH antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity purified

Immunogen: Amino acids A75-E141 from the human protein were used as the immunogen for the AMH antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the AMH antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the AMH antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for AMH

Target: AMH (Anti-Mullerian Hormone (AMH))

Alternative Name: Muellerian Hormone (AMH Products)

Synonyms: AMH antibody, amh antibody, MIF antibody, MIS antibody, anti-Mullerian hormone antibody, amh antibody, AMH antibody, Amh antibody

Background: Anti-Müllerian hormone (AMH), also known as MIF or MIS, is a protein that in humans is encoded by the AMH gene. It is a hormone that inhibits the development of the Müllerian ducts (paramesonephric ducts) in the male embryo. Expression of AMH is activated by SOX9 in the male Sertoli cells and causes the irreversible regression of the Müllerian ducts. Because AMH expression is critical to sex differentiation at a specific time during fetal development, it appears to be tightly regulated by SF1, GATA factors, DAX1 and FSH. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.

UniProt: P03971

Pathways: Negative Regulation of Hormone Secretion