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Betacellulin antibody

BTC Reactivity: Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5708196
  • Target See all Betacellulin (BTC) Antibodies
    Betacellulin (BTC)
    Reactivity
    • 46
    • 33
    • 12
    • 2
    • 1
    Mouse, Rat
    Host
    • 62
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 65
    • 5
    Polyclonal
    Conjugate
    • 33
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Betacellulin antibody is un-conjugated
    Application
    • 62
    • 20
    • 16
    • 13
    • 13
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity purified
    Immunogen
    A rat partial recombinant protein corresponding to amino acids D32-A177 was used as the immunogen for the Betacellulin antibody.
    Isotype
    IgG
    Top Product
    Discover our top product BTC Primary Antibody
  • Application Notes
    Optimal dilution of the Betacellulin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant rat protein) (BSA-free format available)
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the Betacellulin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    Betacellulin (BTC)
    Alternative Name
    Betacellulin / BTC (BTC Products)
    Synonyms
    BTC antibody, LOC100228121 antibody, probetacellulin antibody, Bcn antibody, betacellulin antibody, betacellulin, epidermal growth factor family member antibody, BTC antibody, LOC100228121 antibody, Btc antibody
    Background
    Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
    UniProt
    Q9JJM4
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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