S100A7 antibody

Catalog No. ABIN5708274

Product Details anti-S100A7 Antibody

Target: S100A7 (S100 Calcium Binding Protein A7 (S100A7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: A recombinant human partial protein corresponding to amino acids S2-Q101 was used as the immunogen for the Psoriasin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Psoriasin antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Psoriasin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for S100A7

Target: S100A7 (S100 Calcium Binding Protein A7 (S100A7))

Alternative Name: S100A7 / Psoriasin (S100A7 Products)

Synonyms: PSOR1 antibody, S100A7c antibody, S100A7 antibody, S100 calcium binding protein A7 antibody, protein S100-A7 antibody, S100A7 antibody, LOC469501 antibody, LOC713189 antibody, LOC714943 antibody, LOC101104285 antibody, LOC102191570 antibody

Background: S100 calcium-binding protein A7 (S100A7), also known as psoriasin, is a protein that in humans is encoded by the S100A7 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.

UniProt: P31151

Pathways: S100 Proteins