AGRP antibody

Catalog No. ABIN5708418

Product Details anti-AGRP Antibody

Target: AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGRP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: A recombinant mouse partial protein corresponding to amino acids S82-T131 was used as the immunogen for the AGRP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the AGRP antibody should be determined by the researcher.\. IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the AGRP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for AGRP

Target: AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))

Alternative Name: AGRP (AGRP Products)

Synonyms: AGRT antibody, ART antibody, ASIP2 antibody, Agrt antibody, Art antibody, agouti related neuropeptide antibody, agouti-related protein pseudogene antibody, AGRP antibody, Agrp antibody, LOC100352591 antibody

Background: Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

UniProt: P56473

Pathways: Feeding Behaviour, Photoperiodism