Periaxin antibody

Catalog No. ABIN5708499

Product Details anti-Periaxin Antibody

Target: Periaxin (PRX)

Reactivity: Rat, Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Periaxin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids M1-K91 was used as the immunogen for the Periaxin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Periaxin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Periaxin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Periaxin

Target: Periaxin (PRX)

Alternative Name: Periaxin / PRX (PRX Products)

Synonyms: xprx antibody, MGC89167 antibody, CMT4F antibody, L-Periaxin antibody, periaxin antibody, prx antibody, PRX antibody, Prx antibody

Background: Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

UniProt: Q9BXM0