GRIN3A antibody (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A) (AA 980-1030)

Details for Product anti-GRIN3A Antibody No. ABIN571458
Antigen
Epitope
AA 980-1030
1
1
Reactivity
Human
2
1
Host
Rabbit
2
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
2
1
Options
Immunogen A synthetic peptide from aa region 980-1030 of human NMDAR3A conjugated to blue carrier protein was used as the antigen.
Specificity Specific for NMDAR3A.
Purification Whole serum
Antigen
Alternative Name NMDAR3A (GRIN3A Antibody Abstract)
Background Function: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines. May also play a role in PPP2CB-NMDAR mediated signaling mechanism.
Subcellular location: Cell membrane, Multi-pass membrane protein. Cell junction › synapse › postsynaptic cell membrane. Cell junction › synapse › postsynaptic cell membrane › postsynaptic density. Note: Enriched in post-synaptic plasma membrane and post-synaptic densities. Requires the presence of GRIN1 to be targeted at the plasma membrane.
Tissue specificity: Isoform 1 and isoform 2 are expressed inolfactory bulb, frontal occipital, entorhinal and pyriform cortices, hippocampus, striatum, thalamus, cerebellum and spinal cord. Also known as: NMD3A, Glutamate [NMDA] receptor subunit 3A, Glutamate receptor chi-1, N-methyl-D-aspartate receptor, N-methyl-D-aspartate receptor subtype 3A, NR3A, NMDAR-L, NMDAR-L1.
Pathways Synaptic Membrane
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A (GRIN3A) (AA 980-1030) antibody (ABIN571458) IHC on paraffin sections of human brain tissue using Rabbit antibody to NMDAR3A (980-...
Image no. 2 for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A (GRIN3A) (AA 980-1030) antibody (ABIN571458) IHC on paraffin sections of human brain tissue using Rabbit antibody to NMDAR3A (980-...
Image no. 3 for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A (GRIN3A) (AA 980-1030) antibody (ABIN571458) IHC on paraffin sections of human brain tissue using Rabbit antibody to NMDAR3A (980-...
Image no. 4 for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A (GRIN3A) (AA 980-1030) antibody (ABIN571458) IHC on paraffin sections of human brain tissue using Rabbit antibody to NMDAR3A (980-...