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CHRNA10 antibody (C-Term)

CHRNA10 Reactivity: Human IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN571796
$454.67
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 7 to 8 Business Days
  • Target See all CHRNA10 Antibodies
    CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
    Binding Specificity
    • 9
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 36
    • 12
    • 6
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 35
    • 2
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHRNA10 antibody is un-conjugated
    Application
    • 29
    • 22
    • 20
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    Specific for CHRNA10.
    Cross-Reactivity
    Human
    Cross-Reactivity (Details)
    Other species not yet tested but expected to work in rat and mouse.
    Purification
    Whole serum
    Immunogen
    A synthetic peptide from c-terminal region of human Neuronal acetylcholine receptor subunit alpha-10 conjugated to blue carrier protein was used as the antigen. The antigen shares 85% identity with mouse and rat sequences.
  • Application Notes
    IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 100 μL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
    Alternative Name
    CHRNA10 (CHRNA10 Products)
    Synonyms
    si:dkey-24p1.3 antibody, ALPHA 10 nAChR antibody, cholinergic receptor, nicotinic, alpha polypeptide 10 antibody, cholinergic receptor nicotinic alpha 10 subunit antibody, cholinergic receptor, nicotinic, alpha 10a antibody, neuronal acetylcholine receptor subunit alpha-10 antibody, cholinergic receptor, nicotinic, alpha 10 (neuronal) antibody, Chrna10 antibody, CHRNA10 antibody, chrna10a antibody, LOC100344381 antibody
    Background
    FUNCTION: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. Subcellular location: Cell membrane, Multi-pass membrane protein. Cell junction âÄ° synapse âÄ° postsynaptic cell membrane, Multi-pass membrane protein. Tissue specificity: Expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes.,Auditory,ACH10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10, NACHRA10
    UniProt
    Q9GZZ6
    Pathways
    Sensory Perception of Sound, Synaptic Membrane
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