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ROBO1 antibody (Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila)) (C-Term) Primary Antibody

ROBO1 Reactivity: Mouse IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN572076
$454.67
Plus shipping costs $45.00
100 μL
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  • Target
    ROBO1
    Binding Specificity
    C-Term
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Mouse
    • 35
    • 14
    • 14
    • 3
    • 1
    Host
    Rabbit
    • 23
    • 8
    • 6
    Clonality
    Polyclonal
    • 32
    • 5
    Conjugate
    This ROBO1 antibody is un-conjugated
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (IHC), Western Blotting (WB)
    • 28
    • 24
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Specificity
    Specific for Robo1.
    Purification
    Whole serum
    Immunogen
    A synthetic peptide to from c-terminal region of mouse Robo1 (Roundabout homolog 1) conjugated to an immunogenic carrier protein was used as the antigen.
  • Application Notes
    A dilution of 1: 300 to 1: 2000 is recommended.
    The optimal dilution should be determined by the end user.
    Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    ROBO1
    Alternative Name
    Robo1 (ROBO1 Antibody Abstract)
    Synonyms
    DUTT1, SAX3, AW494633, AW742721, Gm310, ROBO1, dutt1, roundabout, sax3, MGC122264, roundabout-1, roundabout guidance receptor 1, roundabout, axon guidance receptor, homolog 1 (Drosophila), roundabout guidance receptor 1 L homeolog, ROBO1, Robo1, robo1, robo1.L
    Background
    Function: Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.
    Subcellular location: Membrane, Single-pass type I membrane protein
    Tissue specificity: Expressed in embryonal spinal chord. Expressed in embryonal lung, and in adult lung bronchial epithelial cells of large proximal airways. Also known as: Roundabout homolog 1, Dutt1.
    Pathways
    Positive Regulation of Endopeptidase Activity
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