Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1) (1st Cytoplasmic Loop) antibody

Details for Product No. ABIN572226
Antigen
  • HTRP-1
  • TRP1
  • Trrp1
  • xtrpc1
  • Mtrp1
  • Trp1
  • Trpc1
  • transient receptor potential cation channel subfamily C member 1
  • transient receptor potential cation channel, subfamily C, member 1
  • transient receptor potential cation channel, subfamily C, member 1 L homeolog
  • TRPC1
  • Trpc1
  • trpc1.L
  • trpc1
Epitope
1st Cytoplasmic Loop
13
9
7
4
4
4
4
4
2
1
1
1
Reactivity
Rat (Rattus), Mouse (Murine), Human
77
42
32
1
Host
Rabbit
64
9
3
1
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
55
31
17
13
8
6
6
4
2
Options
Immunogen A synthetic peptide from the 1t cytoplasmic loop of rat TRPC1 conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for TRPC1.
Purification Whole serum
Antigen
Alternative Name TRPC1 (TRPC1 Antibody Abstract)
Background Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Subunit: Interacts with TRPC3. Interacts with ITPR3.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Seems to be ubiquitous. Also known as: Short transient receptor potential channel 1, TrpC1, TRP-1 protein, Trp1, Trrp1, Trpc1 transient receptor potential cation channel, subfamily C, member 1, Mtrp1, Trp-related protein 1.
Application Notes A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
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