CAMK2A antibody (AA 455-468)

Catalog No. ABIN574315

Product Details anti-CAMK2A Antibody

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Binding Specificity: AA 455-468

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Pig, Bat, Horse, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This CAMK2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human CAMK2A. This antibody is expected to recognize both reported isoforms (NP_057065.2, NP_741960.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset, Mouse, Rat, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Stickleback, Pufferfish (100%) Hamster, Elephant, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus (93%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-PRTAQSEETRVWHR from an internal region of human CAMK2A (NP_057065.2, NP_741960.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset, Mouse, Rat, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Stickleback, Pufferfish (100%), Hamster, Elephant, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus (93%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:64000), WB (0.1 - 0.3 μg/mL)

Usage: Approx 55+65  kDa bands observed in Human Brain (Cerebellum) and Mouse Brain lysates (calculated MW of 55.3  kDa according to Human NP_057065.2 and of 54.1 according to Human NP_741960.1 and Mouse NP_803126.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.1-0.3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CAMK2A

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Alternative Name: CAMK2A / CaMKII alpha (CAMK2A Products)

Synonyms: camk2 antibody, camk2b antibody, zgc:112538 antibody, zgc:123320 antibody, CAMKA antibody, CaMKII antibody, R74975 antibody, mKIAA0968 antibody, PK2CDD antibody, PKCCD antibody, calcium/calmodulin dependent protein kinase II alpha antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog antibody, calcium/calmodulin-dependent protein kinase II alpha antibody, CAMK2A antibody, camk2a.S antibody, camk2a antibody, Camk2a antibody

Background: Name/Gene ID: CAMK2A
Subfamily: CAMK2
Family: Protein Kinase

Synonyms: CAMK2A, AlphaCaMKII, CaM-kinase II alpha chain, CaMK-II subunit alpha, CAMKA, CaM kinase II alpha, CaMK II alpha, CaMK-II alpha subunit, CaMKIINalpha, CaM kinase II alpha subunit, CaM kinase II subunit alpha, CaMKII alpha, CaMKIIalpha, KIAA0968

Gene ID: 815

NCBI Accession: NP_057065, NP_741960

UniProt: Q9UQM7

Pathways: WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction