TSC1 antibody (AA 1150-1163)

Catalog No. ABIN574381

Product Details anti-TSC1 Antibody

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Binding Specificity: AA 1150-1163

Reactivity: Human, Rat, Dog, Horse, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This TSC1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human TSC1. This antibody is expected to recognise isoform 1 (NP_000359.1) only.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Rat, Panda, Dog, Horse, Platypus (100%) Mouse, Hamster, Turkey (93%) Bat, Rabbit (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-QLHIMDYNETHHEH from the C-terminus of human TSC1 (NP_000359.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Rat, Panda, Dog, Horse, Platypus (100%), Mouse, Hamster, Turkey (93%), Bat, Rabbit (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:128000), WB (0.1 - 0.3 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TSC1

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Alternative Name: Hamartin / TSC1 (TSC1 Products)

Synonyms: LAM antibody, TSC antibody, hamartin antibody, mKIAA0243 antibody, tsc1 antibody, wu:fc38b04 antibody, fa99f04 antibody, wu:fa99f04 antibody, zgc:63657 antibody, TSC complex subunit 1 antibody, tuberous sclerosis 1 antibody, TSC complex subunit 1b antibody, TSC complex subunit 1a antibody, TSC1 antibody, Tsc1 antibody, tsc1b antibody, tsc1 antibody, tsc1a antibody

Background: Name/Gene ID: TSC1

Synonyms: TSC1, LAM, Tuberous sclerosis 1 protein, Tuberous sclerosis 1, Hamartin, KIAA0243, TSC, Tumor suppressor

Gene ID: 7248

NCBI Accession: NP_000359

UniProt: Q92574

Pathways: RTK Signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation