HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 1-242) antibody

Catalog No. ABIN5775951

This Mouse Monoclonal antibody specifically detects in WB, ELISA, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 1-242) antibody (ABIN5775951)

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT5D6

Product Details

Binding Specificity: AA 1-242

Immunogen: Recombinant human HTATIP2 (1-242aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Alternative Name: TIP30/HTATIP2

Background: HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy.