CLEC4E antibody (AA 41-219)

Catalog No. ABIN5776070

This anti-CLEC4E antibody is a Mouse Monoclonal antibody detecting CLEC4E in WB, ELISA, FACS, IF, IHC and ICC. Suitable for Human.

Quick Overview for CLEC4E antibody (AA 41-219) (ABIN5776070)

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CLEC4E antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: AT16E3

Product Details anti-CLEC4E Antibody

Binding Specificity: AA 41-219

Purpose: Human MINCLE/CLEC4E antibody

Immunogen: Recombinant human MINCLE (41-219aa) purified from E.coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for CLEC4E

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Alternative Name: MINCLE/CLEC4E

Background: CLEC4E (macrophage inducible C-type lectin, also called MINCLE or CLECSF9), which is a diverse family of protein which was originally defined by their ability to recognize a wide range of ligand of carbohydrate structure. CLEC4E expressed in macrophages subjected to several types of stress. It plays an essential role in response to trehalose-6, 6'-dimycolate (TDM) and activated by a synthetic analogue, trehalose dibehenate (TDB). Recently it was reported that CLEC4E is associated with an immunoreceptor tyrosine-based activation motif-containing Fc receptor gamma chain (FcRgamma) and functions as an activating receptor for damaged self- and non-self-pathogenic fungi.

NCBI Accession: NP_055173