SLC26A3 antibody

Catalog No. ABIN5957617

Product Details anti-SLC26A3 Antibody

Target: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC26A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Chloride anion exchanger,CLD,Congenital chloride diarrhea,Down regulated in adenoma,Down regulated in adenoma protein,Down-regulated in adenoma,DRA,Protein DRA,S26A3,SLC26A3,Solute carrier family 26 member 3

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the C-terminal region of human DRA.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLC26A3

Target: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Alternative Name: DRA (SLC26A3 Products)

Synonyms: CLD antibody, DRA antibody, 9030623B18Rik antibody, 9130013M11Rik antibody, AV376035 antibody, Dra antibody, si:dkey-31f5.2 antibody, SLC26A3 antibody, solute carrier family 26 member 3 antibody, solute carrier family 26, member 3 antibody, solute carrier family 26 (anion exchanger), member 3 antibody, SLC26A3 antibody, Slc26a3 antibody, slc26a3.1 antibody

Background: The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.SLC26A3 (Solute Carrier Family 26 Member 3) is a Protein Coding gene. Diseases associated with SLC26A3 include Diarrhea 1, Secretory Chloride, Congenital and Congenital Chloride Diarrhea. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Pancreatic secretion. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription cofactor activity. An important paralog of this gene is SLC26A4.

Molecular Weight: 85kDa

Gene ID: 1811

UniProt: P40879