Goosecoid Homeobox 2 (GSC2) antibody

Details for Product No. ABIN5961342
Antigen
  • Gscl
  • GSCL
  • 4930568H22Rik
  • GSC-2
  • goosecoid homeobox 2
  • goosecoid homebox 2
  • Gsc2
  • GSC2
Reactivity
Human, Mouse (Murine)
24
19
4
2
1
1
1
1
1
1
1
1
Host
Rabbit
24
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
16
9
4
3
2
1
1
Options
Immunogen Synthesized peptide derived from the C-terminal region of human GSC2
Isotype IgG
Specificity GSC 2,GSCL,Homeobox protein goosecoid 2,Homeobox protein goosecoid like
Purification Affinity purification
Antigen
Alternative Name GSC2 (GSC2 Antibody Abstract)
Background Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development.GSC2 (Goosecoid Homeobox 2) is a Protein Coding gene. Diseases associated with GSC2 include Digeorge Syndrome and Velocardiofacial Syndrome. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is GSC.
Molecular Weight 22kDa
Gene ID 2928
UniProt O15499
Application Notes WB 1:500-1:2000, ELISA 1:20000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
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