TUSC3 antibody

Catalog No. ABIN5961746

Product Details anti-TUSC3 Antibody

Target: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUSC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: D8S1992,MGC13453,N33,OST3A,Protein N33,Putative prostate cancer tumor suppressor,Tumor suppressor candidate 3,TUSC 3

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the Internal region of human N33

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TUSC3

Target: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Alternative Name: N33 (TUSC3 Products)

Synonyms: zgc:110044 antibody, D8S1992 antibody, M33 antibody, MRT22 antibody, MRT7 antibody, N33 antibody, OST3A antibody, AU022242 antibody, BC003311 antibody, tumor suppressor candidate 3 antibody, tumor suppressor candidate 3 L homeolog antibody, TUSC3 antibody, tusc3 antibody, tusc3.L antibody, CpipJ_CPIJ005611 antibody, Tusc3 antibody

Background: This gene is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene.TUSC3 (Tumor Suppressor Candidate 3) is a Protein Coding gene. Diseases associated with TUSC3 include Autosomal Recessive Non-Syndromic Intellectual Disability and Non-Syndromic Intellectual Disability. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Protein processing in endoplasmic reticulum. GO annotations related to this gene include magnesium ion transmembrane transporter activity and dolichyl-diphosphooligosaccharide-protein glycotransferase activity. An important paralog of this gene is MAGT1.

Molecular Weight: 40kDa

Gene ID: 7991

UniProt: Q13454

Pathways: Cell RedoxHomeostasis