Serotonin Receptor 2B antibody
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- Target See all Serotonin Receptor 2B (HTR2B) Antibodies
- Serotonin Receptor 2B (HTR2B)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Serotonin Receptor 2B antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human HTR2B (NP_000858.3).
- Isotype
- IgG
- Top Product
- Discover our top product HTR2B Primary Antibody
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- Application Notes
- IHC 1:50-1:200 IF 1:10-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Serotonin Receptor 2B (HTR2B)
- Alternative Name
- HTR2B (HTR2B Products)
- Synonyms
- 5-HT2B antibody, 5HT2B antibody, 5htr2b antibody, HTR2B antibody, 5ht2b antibody, zgc:194094 antibody, zgc:194119 antibody, AJ012488 antibody, AV377389 antibody, 5-HT(2B) antibody, 5-hydroxytryptamine receptor 2B antibody, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled antibody, 5-hydroxytryptamine (serotonin) receptor 2B antibody, HTR2B antibody, htr2b antibody, Htr2b antibody
- Background
- This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
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Observed_MW: 55kDa
Calculated_MW: 54kDa
- Gene ID
- 3357
- UniProt
- P41595
- Pathways
- JAK-STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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