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Calpastatin antibody

CAST Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5963194
  • Target See all Calpastatin (CAST) Antibodies
    Calpastatin (CAST)
    Reactivity
    Human, Mouse, Rat
    Host
    • 37
    • 10
    Rabbit
    Clonality
    • 40
    • 7
    Polyclonal
    Conjugate
    • 27
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Calpastatin antibody is un-conjugated
    Application
    • 38
    • 15
    • 13
    • 13
    • 9
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human CAST (NP_001177371.1).
    Isotype
    IgG
    Top Product
    Discover our top product CAST Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Calpastatin (CAST)
    Alternative Name
    CAST (CAST Products)
    Synonyms
    BS-17 antibody, calp3 antibody, CAST antibody, sb:cb966 antibody, zgc:194249 antibody, cast antibody, DKFZp469E0716 antibody, calpastatin antibody, calpastatin S homeolog antibody, Calpastatin antibody, CAST antibody, Cast antibody, cast.S antibody, cast antibody, VDBG_09182 antibody, ical antibody
    Background
    The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
    Molecular Weight

    Observed_MW: 124kDa

    Calculated_MW: 63kDa/71- 84kDa

    Gene ID
    831
    UniProt
    P20810
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